Pimeloyl-acp methyl ester carboxylesterase
WebDec 10, 2024 · The synthesis of methyl ester requires two reiterations of the fatty acid elongation cycle to give a pimeloyl-acyl-carrier protein methyl ester, which is cleaved by BioH, and BioH is a gatekeeper enzyme that blocks elongation of the substrate [ 6, 8 ]. WebFeb 11, 2024 · Pimeloyl-acyl carrier protein (ACP) methyl ester esterase catalyzes the last biosynthetic step of the pimelate moiety of biotin, a key intermediate in biotin …
Pimeloyl-acp methyl ester carboxylesterase
Did you know?
WebMar 9, 2024 · bioH pimeloyl-acyl carrier protein methyl ester esterase [] Gene ID: 947916, updated on 9-Mar-2024 Summary S. marcescens bioH complements Escherichia coli … WebPimeloyl- [acyl-carrier protein] methyl ester esterase (Escherichia coli K-12) Protein Target - PubChem Apologies, we are having some trouble retrieving data from our servers... PUGVIEW FETCH ERROR: 403 Forbidden National Center for Biotechnology Information 8600 Rockville Pike, Bethesda, MD, 20894 USA Contact Policies FOIA
WebDec 9, 2015 · Pimeloyl-ACP methyl ester carboxylesterase Imported Gene names Name bioH Imported ORF names DSOUD_1424 Imported Organism names Organism Desulfuromonas soudanensis Imported Taxonomic identifier 1603606 NCBI Taxonomic lineage Bacteria > Proteobacteria > Deltaproteobacteria > Desulfuromonadales > … WebApr 29, 2024 · The four functional profiles (COG0438, COG1028, COG0451 and COG1595) were the same as those observed for M2, and the bacterial functions COG0535 (radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family), COG0596 (pimeloyl-ACP methyl ester carboxylesterase), COG2814 (predicted arabinose efflux permease, MFS family), …
WebNov 12, 2024 · Genes encoding pimeloyl-ACP methyl ester carboxylesterase and flavin reductase were also detected within the gene cluster. According to Figure 2 A, both genes encoding putative LuxR family transcriptional regulators were detected in the gene clusters of phenol 2-monooxygenase and C12O. WebMay 19, 2024 · Pimeloyl-ACP methyl ester synthesized from P. aeruginosa ACP was also utilized as substrate and gave essentially identical results (data not shown) indicating that the ACP source was...
WebApr 6, 2024 · As shown in Table 1, B2 and B4 belong to the MhpC superfamily, which is annotated as “Pimeloyl-ACP methyl ester carboxylesterase.” B3 belongs to the protocat_pcaD superfamily, which is annotated as “3-oxoadipate enol-lactonase. Note that the substrates are 3-oxoadipate enol-lactone, 2-oxo-2,3-dihydrofuran-5-acetate, 4,5 …
Webpimeloyl- [acyl-carrier protein] methyl ester esterase Reaction catalysed 6-carboxyhexanoyl- [ACP] methyl ester + H2O <=> 6-carboxyhexanoyl- [ACP] + H (+) + methanol Comment (s) Involved in biotin biosynthesis in Gram-negative bacteria. The enzyme exhibits carboxylesterase activity, particularly toward substrates with short acyl chains. drawing down retirement savings calculatorWebAug 6, 2024 · Thus, the biosynthesis of pimeloyl-[ACP] is the only sub-pathway in Fg to synthesize this intermediate compound for subsequent biotin production. This study can serve as the foundation for further … drawing down retirement savingsWebAt this point, BioH hydrolyzes the methyl ester to generate pimeloyl ACP [12]. An alternate pathway for generating pimeloyl ACP has been characterized in B. subtilis. The … employer-provided housing lawsWebHere we report genetic and biochemical definition of P. aeruginosa BioH (PA0502) that functions as a gatekeeper enzyme allowing the product pimeloyl-ACP to exit from fatty acid synthesis cycle... employer prsi thresholdsWebA pimeloyl-ACP methyl ester carboxylesterase, almost fivefold upregulated, functions as a gatekeeper to remove the methyl group from pimeloyl-ACP methyl ester producing pimeloyl-ACP... employer provided housing on w2WebFeb 11, 2024 · Pimeloyl-acyl carrier protein (ACP) methyl ester esterase catalyzes the last biosynthetic step of the pimelate moiety of biotin, a key intermediate in biotin biosynthesis. The paradigm pimeloyl-ACP methyl ester esterase is the BioH protein of Escherichia coli that hydrolyses the ester bond of pimeloyl-ACP methyl ester. drawing down the moon feesemployer providing p45