WebObjective: Glycerol-3-phosphate (Gro3P) phosphatase (G3PP) hydrolyzes Gro3P to glycerol that exits the cell, thereby operating a "glycerol shunt", a metabolic pathway that we identified recently in mammalian cells. We have investigated the role of G3PP and the glycerol shunt in the regulation of glucose metabolism and lipogenesis in mouse liver. WebThe general structure of phosphatidylglycerol consists of a L-glycerol 3-phosphate backbone ester-bonded to either saturated or unsaturated fatty acids on carbons 1 and 2. The head group substituent glycerol is bonded through a phosphomonoester. It is the precursor of surfactant and its presence (>0.3) in the amniotic fluid of the newborn ...
Glycerol-3-Phosphate Acyltransferase - an overview
WebGlycerol-3-phosphate acyltransferases will transfer fatty acids from ACP to either the sn-1 or sn-2 position of glycerol-3-phosphate (G3P), generating phosphatidic acid (1,2 diacyl … WebGlycerol kinase converts glycerol to glycerol-3-phosphate that, in turn, can be converted to dihydroxyacetone phosphate by cytosolic (and/or mitochondrial) glycerol 3-phosphate dehydrogenase. This product can then be converted directly to fructose-1,6-bisphosphate (or through glyceraldehyde-3-phosphate) and then to glucose via the gluconeogenic ... highline warren memphis tennessee
Fast LC-MS quantitation of glucose and glycerol via enzymatic ...
WebGlycerol-3-phosphate acyltransferases will transfer fatty acids from ACP to either the sn-1 or sn-2 position of glycerol-3-phosphate (G3P), generating phosphatidic acid (1,2 diacyl … WebJan 21, 1997 · The deuterium labelling in the glycerol moiety of the phosphatidic acid was 2-3-times higher than in free sn-glycerol-3-phosphate, indicating that a specific pool of sn-glycerol-3-phosphate was used for the synthesis of phosphatidic acid in liver. The results indicate that NADH formed during ethanol oxidation is used in the formation of a pool ... WebDHAP is also the product of the dehydrogenation of L-glycerol-3-phosphate, which is part of the entry of glycerol (sourced from triglycerides) into the glycolytic pathway. Conversely, reduction of glycolysis-derived DHAP to L-glycerol-3-phosphate provides adipose cells with the activated glycerol backbone they require to synthesize new ... highline warren nsm