TīmeklisWe designed and synthesized a new delivery system for the anticancer drug doxorubicin based on a biocompatible hydrophilic poly(2-ethyl-2-oxazoline) (PEtOx) carrier with linear architecture and narrow molar mass distribution. The drug is connected to the polymer backbone via an acid-sensitive hydraz … Tīmeklis2024. gada 20. janv. · Hydrophilic oligo(2-ethyl-2-oxazoline) was chosen here due to its excellent biocompatibility, such as long blood circulation times [43, 44], stealth …
Polyoxazoline: Chemistry, Properties, and Applications in Drug …
TīmeklisThis study aims to explore and evaluate the antitumor efficacy of doxorubicin (DOX)-loaded liposomes containing the novel tri-block polymer folate-poly (2-ethyl-2-oxazoline)-distearoyl phosphatidyl ethanolamine (F-PEOz-DSPE), compared with folate-polyethylene glycol-distearoyl phosphatidyl ethanolamine (F-PEG-DSPE) to … TīmeklisThe postpolymerization modification of polymers produced by living polymerization is an attractive method to create precision nanomaterials. We describe the living cationic ring-opening polymerization of a 2-alkylthio-2-oxazoline to furnish a polythiocarbamate. The polythiocarbamate is activated toward substitution by N- and S-nucleophiles via … changing infocus projector bulb in112a
2-Ethyl-2-oxazoline C5H9NO - PubChem
TīmeklisPolymers based on 2-oxazoline, such as poly(2-ethyl-2-oxazolines) (PETOx), are considered to be a type of 'pseudopeptide' with the ability to form novel biomaterials. The hydrolysis of PETOx was carried out to evaluate its use in biomedical applications. In the present work, PETOx samples with a range of molar masses were prepared by … TīmeklisAmong the oxazoline family, 2-oxazolines (OZOs; IUPAC name: 4,5-dihydrooxazoles) with an endo -imino ether group (–C=N–O–) are most extensively studied so far in … Tīmeklis2011. gada 18. nov. · In this study liquid chromatography at critical conditions for poly(2-ethyl-2-oxazoline)s (PEtOx) has been performed for the first time in order to analyze functional PEtOx homopolymers and block ... harkin experience