Clopidogrel bisulfate ph solubility
Web· Trade name: (S)-(+)-Clopidogrel (sulfate) · Article number: 21002 · CAS Number: 120242-66-6 · EC number: 601-679-1 · Application of the substance / the mixture This product is for research use - Not for human or veterinary diagnostic or therapeutic use. · Details of the supplier of the safety data sheet · Manufacturer/Supplier: Cayman ... WebAug 1, 2024 · The present study aims to improve CB intestinal solubility and absorption through developing a novel stable dry CB pro … Clopidogrel bisulfate (CB) is a golden …
Clopidogrel bisulfate ph solubility
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Webidogrel salt. The solubility of Clopidogrel bisulfate salt at pH 7 is ≈0.01 mg/ml, in pH 7.6 buffer solution an approx-imately 640 fold solubility enhancement was achieved. The … WebObjective: To prepare encapsulated clopidogrel bisulfate (CLP) liposomes so as to deal with the poor water solubility of CLP, and to provide the experimental basis for the development of CLP formulations for intravascular injection. Methods: CLP-loaded liposomes were prepared using thin film hydration/sonication method and pH gradient …
WebpH-dependent solubility with very low solubility at physiological pH, and extremely chemical instability at alkaline pH. [0005] Clopidogrel is a weakly base with pKa of 4.5. … WebClopidogrel bisulfate 120242-66-6 Not Listed C,R34; N,R51/53 38 Microcrystalline cellulose 9004-34-6 232-674-9 Not Listed * Silicon dioxide, colloidal NF 7631-86-9 231 …
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WebNov 17, 1997 · Name Clopidogrel bisulfate Drug Entry Clopidogrel. Clopidogrel is a prodrug of a platelet inhibitor used to reduce the risk of myocardial infarction and stroke. 3,9 Clopidogrel is indicated to reduce the risk of myocardial infarction for patients with non-ST elevated acute coronary syndrome (ACS), patients with ST-elevated myocardial …
WebBackground: Clopidogrel hydrogensulfate is a thienopyridine acting as an important antiplatelet agent alone or in combination with acetyl salicylic acid to prevent … gov of canada my account loginWebMar 3, 2014 · Solubility of clopidogrel bisulfate was determined in distilled water, 4.5 pH acetate buffer, 6.8 pH phosphate buffer and 0.1 N (pH-1.2) hydrochloric acid (HCl). children\u0027s food basket grand rapidsWebFeb 1, 2024 · The empirical formula of Clopidogrel bisulfate is C 16 H 16 ClNO 2 S•H 2 SO 4 and its molecular weight is 419.9. The structural formula is as follows: Clopidogrel bisulfate, USP is a white to off-white powder. It is freely soluble in methanol, practically insoluble in ether. children\u0027s font generatorWebcontains 97.875 mg of Clopidogrel bisulfate which is the molar equivalent of 75 mg of Clopidogrel base [3,4].Clopidogrel Bisulfate is fairly soluble and stable in aqueous solution at low pH, however solubility drops steeply when the solution of pH is above 3. Clopidogrel bisulfate exhibits poor dissolution in gov of can jobsWebClopidogrel bisulfate C16H18ClNO6S2 CID 115366 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, … children\u0027s food deliveryWebClopidogrel hydrogen sulfate C32H36Cl2N2O12S4 CID 139079374 - structure, chemical names, physical and chemical properties, classification, patents, literature ... children\u0027s food and nutrition guidelinesWeband in which any of aforesaid aryl, heterocyclyl, heteroaryl, phenyl or phenoxy groups may optionally be substituted by one or more groups selected from C 1-6 alkyl, C 2-6 alkenyl children\u0027s fonts free for commercial use